新加坡人群中抗人细小病毒B19抗体的低流行率。
Low prevalence of antibody to human parvovirus B19 in Singapore.
作者信息
Matsunaga Y, Goh K T, Utagawa E, Muroi N
机构信息
Department of Epidemiology, National Institute of Health, Tokyo.
出版信息
Epidemiol Infect. 1994 Dec;113(3):537-40. doi: 10.1017/s0950268800068552.
A seroepidemiological survey was conducted in Singapore to assess the prevalence of antibody to human parvovirus B19. Sera were collected from 600 healthy individuals between 6 months and over 50 years of age and tested for IgG antibody against B19 virus by antigen capture indirect immunosorbent assay. The overall seropositivity rate was 16.2%. All the children under 5 years of age were seronegative. Antibody prevalence increased gradually from 3.5% in school children (5-14 years of age) to 7.7% in age group 15-19 years and then to 10.3% in young adults (20-24 years of age). In the age group 25-34 years the prevalence was 28% and in the age group over 35 years 65% had parvovirus B19 antibody. The results of the survey indicate that there has been very low incidence of B19 virus infection in Singapore during the last two decades.
在新加坡进行了一项血清流行病学调查，以评估人细小病毒B19抗体的流行情况。从600名年龄在6个月至50岁以上的健康个体中采集血清，并通过抗原捕获间接免疫吸附试验检测针对B19病毒的IgG抗体。总体血清阳性率为16.2%。所有5岁以下儿童血清学检测均为阴性。抗体流行率从学龄儿童（5 - 14岁）的3.5%逐渐上升至15 - 19岁年龄组的7.7%，然后在年轻成年人（20 - 24岁）中升至10.3%。在25 - 34岁年龄组中流行率为28%，在35岁以上年龄组中65%拥有细小病毒B19抗体。调查结果表明，在过去二十年中，新加坡B19病毒感染的发生率非常低。
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