Barbaro S, Zucca M, Bologna L M, Viano I, Martinotti G, Fonzo D, Dianzani F
G Batteriol Virol Immunol. 1976 Jan-Jun;69(1-6):85-90.
Oral vaccination of 19 human adult volunteers with a killed trivalent E. coli vaccine induced an antibody response detectable either in sera and feces. Production of specific IgA immunoglobulins in the intestine was also observed. Antibody titres reached the highest levels 5-10 days after vaccination and were still detectable in the majority of volunteers about 2 months later.
用一种灭活的三价大肠杆菌疫苗对19名成年志愿者进行口服接种，可在血清和粪便中检测到抗体反应。在肠道中也观察到特异性IgA免疫球蛋白的产生。抗体滴度在接种疫苗后5至10天达到最高水平，大约2个月后在大多数志愿者中仍可检测到。
