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[兔针对致病性大肠杆菌血清型的口服免疫。II. 单价和多价疫苗诱导产生的循环抗体和粪便抗体]

[Oral immunization of rabbits against enteropathogenic serotypes of E. coli. II. Production of circulating and fecal antibodies induced with monovalent and polyvalent vaccines].

作者信息

Barbaro S, Viano I, Varesio L, Bologna Lenti M, Zucca M, Dianzani F

出版信息

G Batteriol Virol Immunol. 1975 Jul-Dec;68(7-12):305-10.

PMID:791739
Abstract

Oral vaccination of rabbits with killed polivalent E. coli vaccines (enteropathogenic strains) induced the production of circulating and fecal antibodies to the large majority of serotypes present in the vaccines. The production of specific IgA immunoglobulins in the intestine was also detected. The titres were in general of the same height as those obtained when individual vaccines were administered singularly.

摘要

用灭活的多价大肠杆菌疫苗(肠道致病菌株)对兔子进行口服接种,可诱导产生针对疫苗中大多数血清型的循环抗体和粪便抗体。还检测到肠道中特异性IgA免疫球蛋白的产生。其滴度总体上与单独接种单一疫苗时所获得的滴度相同。

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