[In vitro evaluation of susceptibility to selected antibiotics of strains of staphylococcus aureus isolated from purulent skin changes].

Resistance to antibiotics of Staphylococcus aureus strains isolated from purulent skin changes during the years 1987-1991 was investigated. The antibiogram was performed by the disc-diffusion method. Susceptibility to penicillin, ampicillin, cloxacillin, gentamicin, doxycycline, erythromycin, tetracycline, and lincomycin was determined. In investigated material during years 1987-1991 high percentage of resistant strains was found in the case of penicillin (from 70% to 66.2%), cloxacillin (66.6%-86.4%) and tetracycline (50%-66.2%). High and rising in time percentage of strains resistant to ampicillin, erythromycin and cephradine was also found. Increase of resistance was also observed with gentamicin (1987--7.1%, 1991--27%) and doxycycline++ (1987--12.7%, 1989--35.3%, 1991--17.6%), while resistance to lincomycin was keeping on a generally equal level within 20% (1987) to 26% (1991). In 1991 susceptibility of 42 strains of Staphylococcus aureus was tested to cefamandole, cefoperazone, cefotaxime, ceftriaxone, cefuroxime, amikacin and netilmicin. No resistant strains to these antibiotics were found.