O'Brien E D, Denton J R
Department of Orthopaedic Surgery, Catholic Medical Center of Brooklyn & Queens, New York.
Orthop Rev. 1994 Aug;23(8):662-4.
Fourteen patients with 15 open tibial fractures were examined retrospectively to compare postoperative infection rates of asymptomatic patients who tested positive or negative for the human immunodeficiency virus antibody (HIVab). All patients were treated with a standard open-fracture protocol. All of the HIVab-positive patients developed postoperative infections. There were five postoperative infections in 4 patients; 3 of the 4 patients were HIVab-positive and 2 of these patients developed chronic osteomyelitis. The only other infection, in an HIVab-negative patient with insulin-dependent diabetes, resolved without complication. All other HIVab-negative patients had no complications. The infection rate for asymptomatic HIVab-positive patients with open tibial fractures was higher than that for HIVab-negative patients in our study. These data suggest that the HIV status of patients with open tibial fractures is relevant to treatment outcome.
对14例伴有15处开放性胫骨骨折的患者进行回顾性检查，以比较人类免疫缺陷病毒抗体（HIVab）检测呈阳性或阴性的无症状患者的术后感染率。所有患者均采用标准的开放性骨折治疗方案。所有HIVab阳性患者均发生术后感染。4例患者出现5次术后感染；4例患者中有3例HIVab阳性，其中2例患者发生慢性骨髓炎。唯一的另一例感染发生在1例患有胰岛素依赖型糖尿病的HIVab阴性患者身上，感染自行消退，未出现并发症。所有其他HIVab阴性患者均无并发症。在我们的研究中，开放性胫骨骨折的无症状HIVab阳性患者的感染率高于HIVab阴性患者。这些数据表明，开放性胫骨骨折患者的HIV状况与治疗结果相关。
