Covert R F
Department of Pediatrics, Wyler Children's Hospital, University of Chicago, Illinois 60637.
Pediatr Cardiol. 1994 Mar-Apr;15(2):81-4. doi: 10.1007/BF00817613.
Two neonates with cardiovascular symptoms associated with intracranial AVM were initially considered to have ductal-dependent congenital heart disease. Prostaglandin E1 (PGE1) infusion, initiated to achieve patency of the ductus arteriosus, produced improved oxygenation and cardiovascular status in both infants. Other vascular effects of PGE1, including pulmonary and extracranial systemic vasodilation, likely accounted for these unique observations in the infants with intracranial AVM. Not only may the signs and symptoms of congenital heart disease be imitated by intracranial AVM, but improved oxygenation and cardiovascular status with PGE1 infusion used for suspected congenital heart disease may be observed as well.
两名患有与颅内动静脉畸形相关心血管症状的新生儿最初被认为患有导管依赖性先天性心脏病。为使动脉导管保持通畅而开始输注前列腺素E1（PGE1），两名婴儿的氧合和心血管状况均得到改善。PGE1的其他血管效应，包括肺和颅外系统性血管舒张，可能是这些颅内动静脉畸形婴儿出现这些独特表现的原因。颅内动静脉畸形不仅可能模仿先天性心脏病的体征和症状，而且在用于疑似先天性心脏病的PGE1输注时，也可能观察到氧合和心血管状况改善。
