Lencioni R, Caramella D, Bartolozzi C
Department of Radiology, University of Pisa, Italy.
Radiology. 1995 Jan;194(1):113-8. doi: 10.1148/radiology.194.1.7997536.
To determine the usefulness of color Doppler ultrasound (US) in the evaluation of the response of hepatocellular carcinoma (HCC) to percutaneous ethanol injection (PEI).
Forty-one patients with 48 lesions 2-5 cm in diameter underwent color Doppler US before and after PEI. Computed tomography (CT), magnetic resonance (MR) imaging, and percutaneous biopsy were also performed to help establish the outcome of therapy.
Before treatment, color signals with an arterial Doppler spectrum were seen in 44 of 48 lesions with a frequency shift of 0.51-4.11 kHz (mean, 1.65 kHz). After PEI, 37 of these lesions showed no color signal and were found to be necrotic at CT, MR imaging, and biopsy. In six of seven lesions containing residual tumor, pulsatile flow was still identified, although the frequency shift was significantly decreased (P = .01).
Color Doppler US proved useful in the assessment of the therapeutic effect of PEI on HCC.
确定彩色多普勒超声（US）在评估肝细胞癌（HCC）经皮乙醇注射（PEI）治疗反应中的作用。
41例患有48个直径为2 - 5 cm病变的患者在PEI治疗前后接受了彩色多普勒超声检查。还进行了计算机断层扫描（CT）、磁共振（MR）成像和经皮活检，以帮助确定治疗结果。
治疗前，48个病变中的44个可见具有动脉多普勒频谱的彩色信号，频移为0.51 - 4.11 kHz（平均1.65 kHz）。PEI治疗后，其中37个病变未显示彩色信号，并且在CT、MR成像和活检中发现为坏死。在7个含有残留肿瘤的病变中的6个中，仍可识别出搏动性血流，尽管频移显著降低（P = 0.01）。
彩色多普勒超声被证明在评估PEI对HCC的治疗效果方面是有用的。
