乳腺动脉钙化：与冠状动脉疾病的关联。研究进行中。
Breast arterial calcification: association with coronary artery disease. Work in progress.
作者信息
Moshyedi A C, Puthawala A H, Kurland R J, O'Leary D H
机构信息
Department of Radiology, Geisinger Medical Center, Danville, PA 17822-2007.
出版信息
Radiology. 1995 Jan;194(1):181-3. doi: 10.1148/radiology.194.1.7997548.
PURPOSE
To assess the association between mammographically detected breast arterial calcification (BAC) and coronary artery disease (CAD) and diabetes mellitus (DM).
MATERIALS AND METHODS
The records of 182 women (aged 39-92 years) who underwent both mammography and coronary arteriography were retrospectively reviewed to determine BAC, CAD, and DM status.
RESULTS
For women aged less than 59 years (under-59 group) (n = 54), nearly all women with BAC (n = 8) had CAD (n = 7) and also had DM (n = 6). For this group, the positive predictive value of BAC for CAD was 0.88 and the negative predictive value was 0.65 (chi 2 = 7.7, P < .05). DM was a confounding variable. The positive predictive value of DM for CAD increased from 0.62 when BAC was absent to 1.00 when BAC was present (standard error of difference, .22; P < .10). No significant association between BAC and CAD was found for women aged 59 years and older (n = 128).
CONCLUSION
BAC in women aged less than 59 years may indicate an additional risk factor for CAD, particularly in diabetic patients.
目的
评估乳腺钼靶检测到的乳腺动脉钙化（BAC）与冠状动脉疾病（CAD）及糖尿病（DM）之间的关联。
材料与方法
回顾性分析182例年龄在39 - 92岁之间同时接受乳腺钼靶检查和冠状动脉造影的女性记录，以确定BAC、CAD和DM状况。
结果
对于年龄小于59岁的女性（59岁以下组）（n = 54），几乎所有有BAC的女性（n = 8）都患有CAD（n = 7）且患有DM（n = 6）。对于该组，BAC对CAD的阳性预测值为0.88，阴性预测值为0.65（卡方 = 7.7，P <.05）。DM是一个混杂变量。DM对CAD的阳性预测值在无BAC时为0.62，有BAC时增加到1.00（差异标准误，.22；P <.10）。对于年龄59岁及以上的女性（n = 128），未发现BAC与CAD之间存在显著关联。
结论
年龄小于59岁女性的BAC可能表明CAD的一个额外危险因素，特别是在糖尿病患者中。
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