对溶组织内阿米巴无菌株的毒力进行可逆性增强的尝试。

An attempt at reversibility and increase of the virulence of axenic strains of Entamoeba histolytica.

作者信息

Gomes M A, Costa A O, Tafuri W L, Silva E F

机构信息

Department of Parasitology, Federal University of Minas Gerais, Belo Horizonte, Brazil.

出版信息

Rev Inst Med Trop Sao Paulo. 1993 Nov-Dec;35(6):503-8. doi: 10.1590/s0036-46651993000600005.

DOI:10.1590/s0036-46651993000600005

PMID:7997753

Abstract

In this study we have tried to verify whether the interaction "in vitro" with bacteria or small pieces of normal hamster liver would modify the pathogenic behavior of axenic strains of E. histolytica: avirulent ones (ICB-32 and ICB-RPS), of attenuated virulence (ICB-CSP and HM1) and of mean virulence (ICB-462). Every attempt to render virulent, recover or increase the virulence of axenic strains of E. histolytica has failed.

摘要

在本研究中，我们试图验证溶组织内阿米巴无菌株（无毒株（ICB - 32和ICB - RPS）、减毒株（ICB - CSP和HM1）以及中等毒力株（ICB - 462））与细菌或正常仓鼠肝小块的“体外”相互作用是否会改变其致病行为。使溶组织内阿米巴无菌株变得有 virulent、恢复或增强其 virulence 的每一次尝试均告失败。（注：原文中virulent和virulence未给出准确中文释义，可根据实际医学含义替换，比如“致病力”等）