Mendes N M, Gómez J D, Araújo N, Zani C L, Katz N
Centro de Pesquisas René Rachou-Fundação Oswaldo Cruz, FIOCRUZ, Brasil.
Rev Inst Med Trop Sao Paulo. 1993 Nov-Dec;35(6):509-13. doi: 10.1590/s0036-46651993000600006.
Aqueous suspensions of fruit's pericarp, leaves, root's bark and seeds of Guaiacum officinale were tested at different concentrations as molluscicide, cercaricide and piscicide. In the laboratory the suspension of fruit's pericarp produced 100% mortality for egg masses of B. glabrata at 100 ppm, for adult snails of Biomphalaria glabrata, B. straminea and B. tenagophila at 20 ppm, for Lebistes reticulatus (fishes) at 5 ppm and Schistosoma mansoni's cercariae at 1 ppm. The ethanolic extract of fruit's pericarp was not active against adult snails of B. glabrata. The lethal dose for adult snails(DL90) of the aqueous suspension of fruit's pericarp after 24 hours exposure, were: 15 ppm for B. glabrata; 14 ppm for B. straminea and 18 ppm for B. tenagophila. The DL90 of aqueous suspensions of root's bark, seeds and leaves were 57 ppm, 33 ppm and 15 ppm, respectively. In the field, B. glabrata adult snail mortality was 68% at 20 ppm and 100% at 40 ppm, when using suspension of fruit's pericarp.
对药用愈创木果实的果皮、叶子、根皮和种子的水悬浮液进行了不同浓度的测试，以评估其作为杀螺剂、杀尾蚴剂和杀鱼剂的效果。在实验室中，果皮悬浮液在100 ppm时对光滑双脐螺的卵块产生100%的死亡率，在20 ppm时对光滑双脐螺、稻草双脐螺和嗜气管双脐螺的成年螺产生100%的死亡率，在5 ppm时对网纹剑尾鱼产生100%的死亡率，在1 ppm时对曼氏血吸虫尾蚴产生100%的死亡率。果皮的乙醇提取物对光滑双脐螺的成年螺没有活性。果皮水悬浮液暴露24小时后对成年螺的致死剂量（DL90）分别为：对光滑双脐螺为15 ppm；对稻草双脐螺为14 ppm；对嗜气管双脐螺为18 ppm。根皮、种子和叶子的水悬浮液的DL90分别为57 ppm、33 ppm和15 ppm。在田间，使用果皮悬浮液时，光滑双脐螺成年螺的死亡率在20 ppm时为68%，在40 ppm时为100%。
