Ninomiya J, Shoji T, Tanaka S, Ikeshita M, Ochi M, Yamauchi S, Yajima T, Yamauchi H, Sugimoto T, Aizawa T
Department of Thoracic and Cardiovascular Surgery, Nippon Medical School, Tokyo, Japan.
Artif Organs. 1994 Sep;18(9):702-5. doi: 10.1111/j.1525-1594.1994.tb03403.x.
The major problems with existing centrifugal pumps are leakage, mechanical trauma, and thrombus formation. In consideration of these problems, a new compact centrifugal pump system was developed. The purpose of this study was to evaluate the new centrifugal pump system clinically. Ten patients underwent open heart surgery with a centrifugal pump or a roller pump. During surgery, hemodynamic and hematological data were obtained. A pulsatile assist device in the pump circuit was used in patients with severe heart disease. There was neither operative death nor hospital mortality, and there was no difference with regard to hemodynamic data between the two groups. The centrifugal pump groups, however, had significantly lower hemolysis, especially during prolonged cardiopulmonary bypass. This centrifugal pump could also create sufficient pulsatile flow with a pulsatile assist device. Postoperative macroscopic and microscopic findings demonstrated the smooth surface of the pump without thrombus formation. This centrifugal pump system might be useful for prolonged cardiopulmonary bypass.
现有离心泵的主要问题包括泄漏、机械损伤和血栓形成。考虑到这些问题，研发了一种新型紧凑型离心泵系统。本研究的目的是对新型离心泵系统进行临床评估。10例患者接受了使用离心泵或滚压泵的心脏直视手术。手术过程中，获取了血流动力学和血液学数据。严重心脏病患者在泵循环中使用了搏动辅助装置。两组均无手术死亡和医院死亡病例，两组之间的血流动力学数据也无差异。然而，离心泵组的溶血明显较低，尤其是在长时间体外循环期间。这种离心泵还可以通过搏动辅助装置产生足够的搏动血流。术后宏观和微观检查结果显示泵表面光滑，无血栓形成。这种离心泵系统可能对长时间体外循环有用。
