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粗糙脉孢菌新型不饱和脂肪酸突变体中的脂肪酸生物合成

Fatty acid biosynthesis in novel ufa mutants of Neurospora crassa.

作者信息

Goodrich-Tanrikulu M, Stafford A E, Lin J T, Makapugay M I, Fuller G, McKeon T A

机构信息

United States Department of Agriculture Agricultural Research Service, Western Regional Research Center, Albany, California 94710.

出版信息

Microbiology (Reading). 1994 Oct;140 ( Pt 10):2683-90. doi: 10.1099/00221287-140-10-2683.

DOI:10.1099/00221287-140-10-2683
PMID:8000539
Abstract

New mutants of Neurospora crassa having the ufa phenotype have been isolated. Two of these mutants, like previously identified ufa mutants, require an unsaturated fatty acid for growth and are almost completely blocked in the de novo synthesis of unsaturated fatty acids. The new mutations map to a different chromosomal location than previously characterized ufa mutations. This implies that at least one additional genetic locus controls the synthesis of unsaturated fatty acids in Neurospora.

摘要

已分离出具有ufa表型的粗糙脉孢菌新突变体。其中两个突变体,与先前鉴定的ufa突变体一样,生长需要不饱和脂肪酸,并且在不饱和脂肪酸的从头合成中几乎完全受阻。新突变定位到的染色体位置与先前表征的ufa突变不同。这意味着至少还有一个基因位点控制粗糙脉孢菌中不饱和脂肪酸的合成。

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Fatty acid biosynthesis in novel ufa mutants of Neurospora crassa.粗糙脉孢菌新型不饱和脂肪酸突变体中的脂肪酸生物合成
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Microbiol Mol Biol Rev. 2004 Mar;68(1):1-108. doi: 10.1128/MMBR.68.1.1-108.2004.
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