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A haemolytic cell-free preparation of Moraxella bovis confers protection against infectious bovine keratoconjunctivitis.

作者信息

Billson F M, Hodgson J L, Egerton J R, Lepper A W, Michalski W P, Schwartzkoff C L, Lehrbach P R, Tennent J M

机构信息

University of Sydney, Department of Animal Health, Camden, NSW, Australia.

出版信息

FEMS Microbiol Lett. 1994 Nov 15;124(1):69-73. doi: 10.1111/j.1574-6968.1994.tb07263.x.

DOI:10.1111/j.1574-6968.1994.tb07263.x
PMID:8001772
Abstract

Protection conferred by a cell-free preparation from a haemolytic Moraxella bovis isolate, UQV 148NF, was compared to an equivalent fraction from a non-haemolytic M. bovis isolate, Gordon 26L3, and to a recombinant DNA-derived pili vaccine. Three groups of ten calves were vaccinated twice with one of the three preparations and, together with ten non-vaccinated calves, challenged with virulent M. bovis isolate Dal 2d. Compared to the control group, significant protection was observed in the group receiving the pili vaccine and the group receiving the preparation from haemolytic isolate, UQV 148NF.

摘要

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