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鞘内注射麻醉剂治疗癌痛——病例报告

Intrathecal narcotics in cancer pain--a case report.

作者信息

Frizelle H, Hannon V, McNicholas M

机构信息

Department of Anaesthesia & Intensive Care, St. Vincent's Hospital, Dublin.

出版信息

Ir J Med Sci. 1994 Jul;163(7):328-30. doi: 10.1007/BF02943077.

DOI:10.1007/BF02943077
PMID:8002257
Abstract

A 61 year old female patient presented with metastatic bone pain three years post mastectomy. Standard oral analgesics and epidural morphine were ineffective in achieving pain control. Her pain was eventually controlled with morphine sulphate 48 mg daily via a self administered intrathecal pump. These devices are being used with increasing frequency and this case report highlights some of the problems encountered in this patient's management.

摘要

一名61岁女性患者在乳房切除术后三年出现转移性骨痛。标准口服镇痛药和硬膜外吗啡均无法有效控制疼痛。她的疼痛最终通过每日48毫克硫酸吗啡经自我给药鞘内泵得以控制。这些装置的使用频率越来越高,本病例报告突出了该患者治疗过程中遇到的一些问题。

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Intrathecal narcotics in cancer pain--a case report.鞘内注射麻醉剂治疗癌痛——病例报告
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本文引用的文献

1
Cancer pain relief using chronic morphine infusion. Early experience with a programmable implanted drug pump.使用慢性吗啡输注缓解癌痛。可编程植入式药物泵的早期经验。
J Neurosurg. 1984 Aug;61(2):302-6. doi: 10.3171/jns.1984.61.2.0302.
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Cancer. 1987 Feb 15;59(4):850-6. doi: 10.1002/1097-0142(19870215)59:4<850::aid-cncr2820590432>3.0.co;2-1.
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High dose of spinal morphine produce a nonopiate receptor-mediated hyperesthesia: clinical and theoretic implications.
大剂量脊髓吗啡可产生非阿片受体介导的感觉过敏:临床及理论意义。
Anesthesiology. 1986 May;64(5):590-7. doi: 10.1097/00000542-198605000-00008.
4
Hyperalgesia and myoclonus with intrathecal infusion of high-dose morphine.
Pain. 1991 Dec;47(3):337-339. doi: 10.1016/0304-3959(91)90225-M.