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使用慢性吗啡输注缓解癌痛。可编程植入式药物泵的早期经验。

Cancer pain relief using chronic morphine infusion. Early experience with a programmable implanted drug pump.

作者信息

Penn R D, Paice J A, Gottschalk W, Ivankovich A D

出版信息

J Neurosurg. 1984 Aug;61(2):302-6. doi: 10.3171/jns.1984.61.2.0302.

Abstract

Fourteen patients were implanted with drug pumps to provide chronic epidural or intrathecal morphine to relieve pain due to cancer. A new programmable pump was used in seven of the patients and a constant infusion device was used in the other seven patients. Results, judged by subjective pain reports (on a 0 to 10 scale), decrease in oral narcotics, and change in activity level, were excellent in eight patients, good in five patients, and poor in one patient. The programmable device has the obvious advantage of being able to vary dose according to patient need and requires less frequent refilling. Four programmable pump failures occurred, two requiring replacement.

摘要

14名患者植入了药物泵,以长期硬膜外或鞘内注射吗啡来缓解癌症引起的疼痛。7名患者使用了新型可编程泵,另外7名患者使用了恒速输注装置。根据主观疼痛报告(0至10分)、口服麻醉药的减少情况以及活动水平的变化来判断,8名患者效果极佳,5名患者效果良好,1名患者效果较差。可编程装置具有能够根据患者需求改变剂量且需要较少频繁重新填充的明显优势。发生了4次可编程泵故障,其中2次需要更换。

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