Truant A L, Hallum J V
Oncology. 1976;33(5-6):241-5. doi: 10.1159/000225155.
Mumps virus antigens were demonstrated in biopsied tissues from Hodgkin's disease patients by indirect immunofluorescence. Impression smears from ten lymph node and two spleen specimens revealed viral antigens in the nucleus, cytoplasm or both. Measles virus antigens were detected in six out of seven Hodgkin's disease tissue (lymph nodes) both in the nucleus and cytoplasm. All tissues tested for the presence of Newcastle disease virus (NDV, an avian paramyxovirus) antigens were negative. Control tissues were obtained from patients with non-Hodgkin's lymphomas, breast cancers, adenocarcinomas and a number of other disease processes. In control tissues mumps antigens were detected in seven out of 31 specimens and measles antigens in nine out of 18 tissues.
通过间接免疫荧光法在霍奇金病患者的活检组织中检测到腮腺炎病毒抗原。对10个淋巴结和2个脾脏标本制作的印片检查显示，病毒抗原存在于细胞核、细胞质或两者中。在7个霍奇金病组织（淋巴结）中的6个中，在细胞核和细胞质中均检测到麻疹病毒抗原。所有检测新城疫病毒（NDV，一种禽副粘病毒）抗原的组织均为阴性。对照组织取自非霍奇金淋巴瘤、乳腺癌、腺癌和许多其他疾病患者。在对照组织中，31个标本中有7个检测到腮腺炎抗原，18个组织中有9个检测到麻疹抗原。
