大肠杆菌中与mar位点相关的诱导型多重抗生素抗性的遗传需求分析。
Analysis of the genetic requirements for inducible multiple-antibiotic resistance associated with the mar locus in Escherichia coli.
作者信息
Sulavik M C, Gambino L F, Miller P F
机构信息
Therapeutics Department, Parke-Davis Pharmaceutical Research Division of Warner-Lambert Co., Ann Arbor, Michigan 48106-1047.
出版信息
J Bacteriol. 1994 Dec;176(24):7754-6. doi: 10.1128/jb.176.24.7754-7756.1994.
Abstract
A series of novel genetic constructs derived from the marRAB operon was used to determine the role of this gene cluster in salicylate-inducible multiple-antibiotic resistance in Escherichia coli. Our findings indicate that regulated antibiotic resistance associated with this locus requires only the products of marR and marA, without any neighboring genes.
摘要
一系列源自marRAB操纵子的新型基因构建体被用于确定该基因簇在大肠杆菌水杨酸盐诱导的多重抗生素抗性中的作用。我们的研究结果表明，与该位点相关的受调控抗生素抗性仅需要marR和marA的产物，而不需要任何相邻基因。
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本文引用的文献
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