Damasceno B P, de Capitani E M
Faculdade de Ciências Médicas (FCM), Universidade Estadual de Campinas (UNICAMP), SP, Brasil.
Arq Neuropsiquiatr. 1994 Mar;52(1):90-2. doi: 10.1590/s0004-282x1994000100017.
A 31-year-old woman presented slowly progressing ataxia and neurasthenic symptoms after 14-year occupational exposure to low concentration toluene vapour. Examination disclosed only cerebellar signs. Cognitive functions were normal except moderate visuo-spatial and constructive deficit. CT imaging showed severe pancerebellar atrophy without pathological signs in other brain structures. Two years after she was removed from workplace, CT imaging and ataxia showed no worsening, while visuo-constructive function improved. The authors warn against possible neurotoxic risk associated with this kind of exposure.
一名31岁女性在14年职业接触低浓度甲苯蒸气后出现缓慢进展的共济失调和神经衰弱症状。检查仅发现小脑体征。认知功能正常,但存在中度视觉空间和结构能力缺陷。CT成像显示严重的全小脑萎缩,其他脑结构无病理体征。她脱离工作场所两年后,CT成像和共济失调未加重,而视觉结构功能有所改善。作者警告这种接触可能存在的神经毒性风险。