Wang F, Quigley H A, Tielsch J M
Dana Center for Preventive Ophthalmology, Wilmer Ophthalmological Institute, Johns Hopkins University, Baltimore, Md.
Arch Ophthalmol. 1994 Jun;112(6):796-800. doi: 10.1001/archopht.1994.01090180094042.
To evaluate nerve fiber layer photography as a method for glaucoma screening in a general medical clinic setting.
One hundred seventy-one persons who attended an academic hospital medical clinic were administered a questionnaire and underwent a complete eye examination, including automated perimetry and photography of the optic disc and nerve fiber layer.
Eighteen patients were diagnosed as having primary glaucoma; one, secondary glaucoma; and 21 were suspected of having glaucoma. Nerve fiber layer photographs were taken on 145 persons (85%) and were readable in 136 (80%) of the sample of 171 subjects. Nerve fiber layer atrophy was detected on masked evaluation in 64% of those with glaucoma, in 28% of those suspected of having glaucoma, and in 16% of persons who did not meet the criteria for glaucoma.
Nerve fiber layer photography can be carried out as a screening method and can identify a substantial proportion of those with glaucoma. It compares favorably with tonometry, cup-disc ratio estimation, or screening visual field examination for glaucoma detection.
评估神经纤维层摄影术作为普通内科门诊青光眼筛查方法的效果。
对171名到学术医院内科门诊就诊的患者进行问卷调查，并接受全面的眼部检查，包括自动视野检查以及视盘和神经纤维层摄影。
18例患者被诊断为原发性青光眼；1例为继发性青光眼；21例疑似青光眼。145人（85%）拍摄了神经纤维层照片，在171名受试者样本中有136人（80%）的照片可读。在盲法评估中，64%的青光眼患者、28%的疑似青光眼患者以及16%不符合青光眼标准的人检测到神经纤维层萎缩。
神经纤维层摄影术可作为一种筛查方法，能识别出相当比例的青光眼患者。与眼压测量、杯盘比评估或青光眼检测的筛查视野检查相比，效果良好。
