Ramis A, Majó N, Pumarola M, Fondevila D, Ferrer L
Department of Pathology, School of Veterinary Medicine, Autonomous University of Barcelona, Bellaterra.
Avian Dis. 1994 Jan-Mar;38(1):197-200.
Two cases of naturally occurring fatal disease in eagles (a booted eagle and a buzzard) are reported. Both eagles showed anorexia, weight loss, weakness, and inability to fly. Microscopically, stained liver sections showed wide non-zonal coagulation necrosis and eosinophilic intranuclear inclusion bodies in hepatocytes adjacent to the edges of necrotic regions. Ultrastructural studies of hepatocytes revealed multiple enveloped viral particles in the cytoplasm, focal paracrystalline arrays of virions within the nuclei, and some budding particles bound by a membrane, located in an evagination of nuclear membrane. The size and morphology of all of these particles were consistent with herpesvirus. To our knowledge, this is the first report of naturally occurring field cases of herpesvirus hepatitis in eagles (Accipitridae).
报告了两例鹰（一只靴隼雕和一只普通鵟）自然发生的致命疾病病例。两只鹰均表现出厌食、体重减轻、虚弱和无法飞行。显微镜下，肝脏染色切片显示广泛的非带状凝固性坏死，以及坏死区域边缘相邻肝细胞中的嗜酸性核内包涵体。肝细胞的超微结构研究显示，细胞质中有多个包膜病毒颗粒，细胞核内有病毒粒子的局灶性晶格状排列，以及一些由膜包裹的出芽颗粒，位于核膜的内陷处。所有这些颗粒的大小和形态均与疱疹病毒一致。据我们所知，这是鹰科动物中自然发生的疱疹病毒性肝炎野外病例的首次报告。
