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Soluble receptors for cytokines and growth factors: generation and biological function.

作者信息

Rose-John S, Heinrich P C

机构信息

Institut für Biochemie der Rheinisch-Westfälischen Technischen Hochschule Aachen, Germany.

出版信息

Biochem J. 1994 Jun 1;300 ( Pt 2)(Pt 2):281-90. doi: 10.1042/bj3000281.

DOI:10.1042/bj3000281
PMID:8002928
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1138158/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/9c5358d88199/biochemj00086-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/28626959d3e8/biochemj00086-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/f77012d59bbe/biochemj00086-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/e06cc02eb873/biochemj00086-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/9c5358d88199/biochemj00086-0017-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/28626959d3e8/biochemj00086-0014-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/f77012d59bbe/biochemj00086-0015-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/e06cc02eb873/biochemj00086-0016-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e9f/1138158/9c5358d88199/biochemj00086-0017-a.jpg

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Identification of a soluble receptor for platelet-derived growth factor in cell-conditioned medium and human plasma.在细胞条件培养基和人血浆中鉴定血小板衍生生长因子的可溶性受体。
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2
Serum soluble interleukin-6 receptor in MRL/lpr mice is elevated with age and mediates the interleukin-6 signal.MRL/lpr小鼠血清中的可溶性白细胞介素-6受体水平随年龄增长而升高，并介导白细胞介素-6信号。
Eur J Immunol. 1993 May;23(5):1078-82. doi: 10.1002/eji.1830230515.
3
Structure-function analysis of human IL-6 receptor: dissociation of amino acid residues required for IL-6-binding and for IL-6 signal transduction through gp130.
Cells. 2025 May 22;14(11):766. doi: 10.3390/cells14110766.
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More and more pleiotropy within the IL-6 family of cytokines.白细胞介素-6细胞因子家族中越来越多的基因多效性。
FEBS J. 2025 Feb;292(3):519-522. doi: 10.1111/febs.17355. Epub 2024 Dec 13.
5
Exploring the therapeutic potential of interleukin-6 receptor blockade in autoimmune diseases using drug target mendelian randomization.利用药物靶点孟德尔随机化探索白细胞介素 6 受体阻断在自身免疫性疾病中的治疗潜力。
Immunogenetics. 2024 Nov 26;77(1):3. doi: 10.1007/s00251-024-01360-w.
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A New IL-6-Inducing Mechanism in Cancer with New Therapeutic Possibilities.癌症中一种新的白细胞介素-6诱导机制及新的治疗可能性
Cancers (Basel). 2024 Oct 24;16(21):3588. doi: 10.3390/cancers16213588.
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J Neuroinflammation. 2024 Sep 18;21(1):230. doi: 10.1186/s12974-024-03223-3.
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