Karlson E W, Sudarsky L, Ruderman E, Pierson S, Scott M, Helfgott S M
Brigham and Women's Hospital, Boston, Massachusetts.
Arthritis Rheum. 1994 Jun;37(6):915-8. doi: 10.1002/art.1780370621.
To evaluate the efficacy of intravenous immune globulin (IVIG) in the treatment of stiff-man syndrome (SMS).
An open, unblinded study of 3 patients with active disease and/or disease refractory to treatment with diazepam and/or corticosteroids.
All 3 bedridden patients improved substantially shortly after infusion with IVIG and regained function.
IVIG may be useful for the treatment of SMS.
评估静脉注射免疫球蛋白（IVIG）治疗僵人综合征（SMS）的疗效。
对3例患有活动性疾病和/或对地西泮和/或皮质类固醇治疗难治性疾病的患者进行了一项开放、非盲法研究。
所有3例卧床患者在输注IVIG后不久均有显著改善并恢复了功能。
IVIG可能对SMS的治疗有用。
