Vangsness C T, Akl Y, Marshall G J, Subin W, Smith C F
Department of Orthopaedic Surgery, University of Southern California School of Medicine, Los Angeles.
Arthroscopy. 1994 Apr;10(2):201-5. doi: 10.1016/s0749-8063(05)80094-5.
Thirty mature New Zealand white rabbits were divided into four surgical groups, and a 3- to 4-mm incision was made in the inner avascular zone of the central third of the medial meniscus. In group I, the tear was not treated by lasering or suturing. In group II, the tear was sutured. Group III was given four different doses of the neodymium:yttrium-aluminum-garnet (Nd:YAG) laser irradiation with no suturing. Group IV underwent meniscal suturing followed by the same four different laser irradiation doses. The animals were killed at 2, 4, and 6 weeks, with gross and histologic evaluation of the healing responses by group and time. The overall results showed no healing of this meniscal tear in the avascular zone. Suturing generally showed increased cellular infiltration. The varying doses of the Nd:YAG lasing demonstrated no gradient effect, and no "welding" of menisci was noted. The maximum cellular inflammatory response was noted in the sutured and lased menisci, reinforcing the importance of a stable meniscal environment for healing meniscal tears.
30只成年新西兰白兔被分为四个手术组，在内侧半月板中部三分之一的无血管区内做一个3至4毫米的切口。在第一组中，撕裂处未进行激光治疗或缝合。在第二组中，撕裂处进行了缝合。第三组接受了四种不同剂量的钕钇铝石榴石（Nd:YAG）激光照射，未进行缝合。第四组先进行半月板缝合，然后接受相同的四种不同激光照射剂量。在2周、4周和6周时处死动物，按组和时间对愈合反应进行大体和组织学评估。总体结果显示，无血管区内的这种半月板撕裂未愈合。缝合通常显示细胞浸润增加。不同剂量的Nd:YAG激光照射未显示出梯度效应，也未观察到半月板的“焊接”现象。在缝合和激光照射的半月板中观察到最大的细胞炎症反应，这强化了稳定的半月板环境对半月板撕裂愈合的重要性。
