Shimura T, Yamamoto T, Shimokochi M
Department of Behavioral Physiology, Faculty of Human Sciences, Osaka University, Japan.
Brain Res. 1994 Mar 21;640(1-2):215-22. doi: 10.1016/0006-8993(94)91875-9.
A total of 74 single unit activities was recorded from the medial preoptic-anterior hypothalamic continuum (MPOA) during free copulatory behavior of male rats. Forty-six units (62.2%) showed changed activities during at least one phase of male copulatory movements; 26 units (35.1%) increased in the firing rate during pelvic thrusting; 32 units (43.2%) increased in activity during backward jumping immediately after intromission; only one unit (1.4%) showed decreased firing rate during thrusting and backward jumping; 12 units (16.2%) increased in activity during pursuit of a female; 19 units (25.7%) were suppressed during genital grooming. Furthermore, 67 units (90.5%) showed a significant change in activity throughout a series of copulatory behavior. From the introduction of a female up to ejaculation, relatively large number of units increased in the firing rate above the value during pre-introduction adaptation period. During postejaculatory interval, however, most units decreased in activity below the level during copulation. These results strongly suggest that the MPOA is involved in both sexual arousal and performance in male rats.
在雄性大鼠自由交配行为期间，从内侧视前区 - 下丘脑前部连续区域（MPOA）共记录到74个单神经元活动。46个神经元（62.2%）在雄性交配动作的至少一个阶段表现出活动变化；26个神经元（35.1%）在骨盆 thrusting 期间放电频率增加；32个神经元（43.2%）在插入后立即向后跳跃期间活动增加；只有1个神经元（1.4%）在 thrusting 和向后跳跃期间放电频率降低；12个神经元（16.2%）在追逐雌性期间活动增加；19个神经元（25.7%）在生殖器梳理期间受到抑制。此外，67个神经元（90.5%）在一系列交配行为中活动出现显著变化。从引入雌性到射精，相对大量的神经元放电频率增加至高于引入前适应期的值。然而，在射精后间隔期间，大多数神经元活动降至交配期间的水平以下。这些结果有力地表明，MPOA参与雄性大鼠的性唤起和性行为表现。 （注：文中thrusting未找到合适中文对应，保留英文）
