杜克雷嗜血杆菌产生的溶血活性的鉴定。
Identification of a hemolytic activity elaborated by Haemophilus ducreyi.
作者信息
Palmer K L, Grass S, Munson R S
机构信息
Edward Mallinckrodt Department of Pediatrics, Washington University School of Medicine, St. Louis, Missouri.
出版信息
Infect Immun. 1994 Jul;62(7):3041-3. doi: 10.1128/iai.62.7.3041-3043.1994.
Abstract
Haemophilus ducreyi is the causative agent of the sexually transmitted disease chancroid. We have identified a hemolytic activity expressed by H. ducreyi. This activity is most readily detected when horse erythrocytes are used as a target; however, low levels of activity can be detected with sheep, human, or rabbit erythrocyte targets. The activity is heat labile and protease sensitive.
摘要
杜克雷嗜血杆菌是性传播疾病软下疳的病原体。我们已经鉴定出杜克雷嗜血杆菌表达的一种溶血活性。当使用马红细胞作为靶标时，这种活性最容易检测到；然而，使用绵羊、人或兔红细胞靶标时也能检测到较低水平的活性。该活性对热不稳定且对蛋白酶敏感。
相似文献
1
Identification of a hemolytic activity elaborated by Haemophilus ducreyi.杜克雷嗜血杆菌产生的溶血活性的鉴定。
Infect Immun. 1994 Jul;62(7):3041-3. doi: 10.1128/iai.62.7.3041-3043.1994.
2
Characterization of the hemolytic activity of Haemophilus ducreyi.杜克雷嗜血杆菌溶血活性的鉴定
Infect Immun. 1995 Nov;63(11):4409-16. doi: 10.1128/iai.63.11.4409-4416.1995.
3
Prevalence of, antibody response to, and immunity induced by Haemophilus ducreyi hemolysin.杜克雷嗜血杆菌溶血素的患病率、抗体反应及诱导的免疫
Infect Immun. 1999 Jul;67(7):3317-28. doi: 10.1128/IAI.67.7.3317-3328.1999.
4
Haemophilus ducreyi hemolysin acts as a contact cytotoxin and damages human foreskin fibroblasts in cell culture.杜克雷嗜血杆菌溶血素作为一种接触性细胞毒素，在细胞培养中会损伤人包皮成纤维细胞。
Infect Immun. 1996 Jun;64(6):2349-52. doi: 10.1128/iai.64.6.2349-2352.1996.
5
Target cell range of Haemophilus ducreyi hemolysin and its involvement in invasion of human epithelial cells.杜克雷嗜血杆菌溶血素的靶细胞范围及其在侵袭人上皮细胞中的作用。
Infect Immun. 1999 Aug;67(8):3740-9. doi: 10.1128/IAI.67.8.3740-3749.1999.
6
Mechanisms of skin adherence, penetration and tissue necrosis production by Haemophilus ducreyi, the causative agent of chancroid.软下疳病原体杜克雷嗜血杆菌导致皮肤黏附、穿透及组织坏死的机制。
Acta Derm Venereol Suppl (Stockh). 1992;174:1-20.
7
Biology of Haemophilus ducreyi.杜克雷嗜血杆菌生物学
Microbiol Rev. 1989 Dec;53(4):377-89. doi: 10.1128/mr.53.4.377-389.1989.
8
A temperature-dependent rabbit model for production of dermal lesions by Haemophilus ducreyi.一种用于研究杜克雷嗜血杆菌产生皮肤损伤的温度依赖性兔模型。
J Infect Dis. 1991 Aug;164(2):359-67. doi: 10.1093/infdis/164.2.359.
9
Haemophilus ducreyi inhibits phagocytosis by U-937 cells, a human macrophage-like cell line.杜克雷嗜血杆菌可抑制U-937细胞（一种人巨噬细胞样细胞系）的吞噬作用。
Infect Immun. 2001 Aug;69(8):4726-33. doi: 10.1128/IAI.69.8.4726-4733.2001.
10
The cytolethal distending toxin of Haemophilus ducreyi aggravates dermal lesions in a rabbit model of chancroid.杜克雷嗜血杆菌的细胞致死性膨胀毒素会加重软下疳兔模型中的皮肤损伤。
Microbes Infect. 2005 May;7(5-6):867-74. doi: 10.1016/j.micinf.2005.02.009. Epub 2005 Apr 20.
引用本文的文献
1
Haemophilus ducreyi targets Src family protein tyrosine kinases to inhibit phagocytic signaling.杜克雷嗜血杆菌靶向Src家族蛋白酪氨酸激酶以抑制吞噬信号传导。
Infect Immun. 2005 Dec;73(12):7808-16. doi: 10.1128/IAI.73.12.7808-7816.2005.
2
Differential expression of porins OmpP2A and OmpP2B of Haemophilus ducreyi.杜克雷嗜血杆菌孔蛋白OmpP2A和OmpP2B的差异表达
Infect Immun. 2004 Nov;72(11):6271-8. doi: 10.1128/IAI.72.11.6271-6278.2004.
3
A CdtA-CdtC complex can block killing of HeLa cells by Haemophilus ducreyi cytolethal distending toxin.CdtA-CdtC复合物可阻断杜克雷嗜血杆菌细胞致死性膨胀毒素对HeLa细胞的杀伤作用。
Infect Immun. 2003 Nov;71(11):6633-40. doi: 10.1128/IAI.71.11.6633-6640.2003.
4
Haemophilus ducreyi inhibits phagocytosis by U-937 cells, a human macrophage-like cell line.杜克雷嗜血杆菌可抑制U-937细胞（一种人巨噬细胞样细胞系）的吞噬作用。
Infect Immun. 2001 Aug;69(8):4726-33. doi: 10.1128/IAI.69.8.4726-4733.2001.
5
Cloning, overexpression, purification, and immunobiology of an 85-kilodalton outer membrane protein from Haemophilus ducreyi.杜克雷嗜血杆菌85千道尔顿外膜蛋白的克隆、过表达、纯化及免疫生物学研究
Infect Immun. 2001 Jul;69(7):4438-46. doi: 10.1128/IAI.69.7.4438-4446.2001.
6
Expression of cytolethal distending toxin and hemolysin is not required for pustule formation by Haemophilus ducreyi in human volunteers.杜克雷嗜血杆菌在人类志愿者中形成脓疱并不需要细胞致死性膨胀毒素和溶血素的表达。
Infect Immun. 2001 Mar;69(3):1938-42. doi: 10.1128/IAI.69.3.1938-1942.2001.
7
Construction and characterization of Haemophilus ducreyi lipooligosaccharide (LOS) mutants defective in expression of heptosyltransferase III and beta1,4-glucosyltransferase: identification of LOS glycoforms containing lactosamine repeats.杜克雷嗜血杆菌七糖基转移酶III和β1,4-葡萄糖基转移酶表达缺陷的脂寡糖（LOS）突变体的构建与鉴定：含乳糖胺重复序列的LOS糖型的鉴定
Infect Immun. 2000 Jun;68(6):3352-61. doi: 10.1128/IAI.68.6.3352-3361.2000.
8
Cloning and characterization of the lipooligosaccharide galactosyltransferase II gene of Haemophilus ducreyi.杜克雷嗜血杆菌脂寡糖半乳糖基转移酶II基因的克隆与鉴定
J Bacteriol. 2000 Apr;182(8):2292-8. doi: 10.1128/JB.182.8.2292-2298.2000.
9
Cytolethal distending toxin of Haemophilus ducreyi induces apoptotic death of Jurkat T cells.杜克雷嗜血杆菌的细胞致死性膨胀毒素可诱导Jurkat T细胞发生凋亡性死亡。
Infect Immun. 1999 Dec;67(12):6394-402. doi: 10.1128/IAI.67.12.6394-6402.1999.
10
Characterization of a Haemophilus ducreyi mutant deficient in expression of cytolethal distending toxin.一株细胞致死性膨胀毒素表达缺陷的杜克雷嗜血杆菌突变体的特性分析
Infect Immun. 1999 Aug;67(8):3900-8. doi: 10.1128/IAI.67.8.3900-3908.1999.
本文引用的文献
1
V.D.R.L. chancroid studies. I. A simple procedure for the isolation and identification of Hemophilus ducreyi.性病研究实验室玻片试验（V.D.R.L.）与软下疳研究。一、一种分离和鉴定杜克雷嗜血杆菌的简单方法。
J Invest Dermatol. 1956 May;26(5):399-406. doi: 10.1038/jid.1956.51.
2
Isolation and identification of Haemophilus ducreyi in a clinical study.一项临床研究中杜克雷嗜血杆菌的分离与鉴定
J Clin Microbiol. 1980 Aug;12(2):170-4. doi: 10.1128/jcm.12.2.170-174.1980.
3
Human immunodeficiency virus infection among men with sexually transmitted diseases. Experience from a center in Africa.患有性传播疾病的男性中的人类免疫缺陷病毒感染。来自非洲一个中心的经验。
N Engl J Med. 1988 Aug 4;319(5):274-8. doi: 10.1056/NEJM198808043190504.
4
Chancroid and Haemophilus ducreyi.软下疳与杜克雷嗜血杆菌。
Clin Microbiol Rev. 1989 Apr;2(2):137-57. doi: 10.1128/CMR.2.2.137.
5
6
Characterization of skin lesions in mice following intradermal inoculation of Haemophilus ducreyi.皮内接种杜克雷嗜血杆菌后小鼠皮肤损伤的特征
J Exp Pathol (Oxford). 1990 Apr;71(2):233-44.
7
Chancroid and the role of genital ulcer disease in the spread of human retroviruses.
Med Clin North Am. 1990 Nov;74(6):1417-31. doi: 10.1016/s0025-7125(16)30488-6.
8
Actinobacillus pleuropneumoniae hlyX gene homology with the fnr gene of Escherichia coli.胸膜肺炎放线杆菌hlyX基因与大肠杆菌fnr基因的同源性。
J Bacteriol. 1990 Aug;172(8):4587-92. doi: 10.1128/jb.172.8.4587-4592.1990.
9
Pore-forming cytolysins of gram-negative bacteria.革兰氏阴性菌的成孔细胞溶素
Mol Microbiol. 1991 Mar;5(3):521-8. doi: 10.1111/j.1365-2958.1991.tb00723.x.
10
Cofactors in male-female sexual transmission of human immunodeficiency virus type 1.1型人类免疫缺陷病毒男女间性传播的辅助因子
J Infect Dis. 1991 Feb;163(2):233-9. doi: 10.1093/infdis/163.2.233.
Zotero 插件