Inoue M, Nakamura J
Department of Neuropsychiatry, Ohmuta City Hospital.
Nihon Rinsho. 1994 May;52(5):1239-44.
We explained about sleep deprivation (SD) and continuous sleep treatment (CST) such as nonpharmacological approaches for depression. Total sleep deprivation (TSD) showed dramatic, but transient, improvement in severe depression following one or more nights of SD. We reported the effects of TSD on 8 depressives. Consequently, after the TSD, the patients were divided into the groups of 3 responders and 5 non-responders in the score of on the basis of a 50% reduction in the score of Hamilton Rating Scale. The minimum rectal temperature (RT) of the non-responders was significant higher on the TSD night compared to the baseline night, but no significant change was observed in the responders. In addition, the minimum nocturnal RT of the responders before TSD tended to be higher. Nowadays, it is not so popular to use CST for depression because the technique is difficult.
我们解释了睡眠剥夺(SD)和持续睡眠治疗(CST),比如治疗抑郁症的非药物方法。完全睡眠剥夺(TSD)在经历一晚或多晚的SD后,对重度抑郁症有显著但短暂的改善效果。我们报告了TSD对8名抑郁症患者的影响。因此,在TSD之后,根据汉密尔顿抑郁量表评分降低50%,将患者分为3名有反应者和5名无反应者两组。无反应者在TSD当晚的最低直肠温度(RT)显著高于基线当晚,但有反应者未观察到显著变化。此外,TSD前有反应者的最低夜间RT往往更高。如今,由于该技术难度大,CST在治疗抑郁症方面不太常用。