[卤泛群的心脏并发症：20例患者的动态心电图研究（动态心电图监测）]

[Cardiac complications of halofantrine: continuous electrocardiographic study (holter) in 20 patients].

作者信息

Monlun E, Le Metayer P, Receveur M C, Bouabdallah K, Neau D, Longy-Boursier M, Le Bras M

机构信息

Clinique médicale propédeutique, médecine interne et maladies tropicales, hôpital Saint André, CHU Bordeaux, France.

出版信息

Rev Med Interne. 1993;14(10):954. doi: 10.1016/s0248-8663(05)80072-4.

DOI:10.1016/s0248-8663(05)80072-4

PMID:8009050

Abstract

Three cases of long QT-interval due to halofantrine were documented in 1992 in France. Two of them had a congenital long QT-interval (Romano-Ward syndrome). We performed a prospective study of cardiac monitoring in 20 patients taking halofantrine. Minimal ECG changes were noted with lengthening of the QT-interval. Systematic ECG is necessary before giving halofantrine.

摘要

1992年在法国记录了3例由卤泛群引起的长QT间期病例。其中2例患有先天性长QT间期（ Romano-Ward综合征）。我们对20名服用卤泛群的患者进行了心脏监测的前瞻性研究。随着QT间期延长，观察到最小的心电图变化。在给予卤泛群之前，系统的心电图检查是必要的。