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关于“大肠杆菌”菌株中金属抗性与接合转移的研究（作者译）

[Researches on metal-resistance and conjugation-transfer in "Escherichia coli" strains (author's transl)].

作者信息

Rizzo G

出版信息

Ann Sclavo. 1976 Nov-Dec;18(6):831-40.

PMID:800943
Abstract

The resistance for HgCl2, NaAsO2, Co(NO3)2, NiSO4, ZnSO4, Agtno3, and CdSO4 in 40 strains of Escherichia coli, was investigated. In 16 of 23 Hg-resistant strains, resistance transfer was obtained by means of conjugation with Salmonella typhi. Hg-resistance was present only in antibiotic-resistant strains, but no correlation was possible with any antibiotic-resistance determinants: because Hg-resistance transfer may occur independently, and it is possible to obtain clones spontaneously segregant for the mentioned trait. As for the possible mechanisms of bacterial metal-resistance, several hypothesis were prospected, the most credible one that of a detoxification of the metallic salt.

摘要

研究了40株大肠杆菌对HgCl2、NaAsO2、Co(NO3)2、NiSO4、ZnSO4、AgNO3和CdSO4的抗性。在23株耐汞菌株中的16株中，通过与伤寒沙门氏菌接合获得了抗性转移。耐汞性仅存在于抗生素抗性菌株中，但与任何抗生素抗性决定因素均无相关性：因为耐汞性转移可能独立发生，并且有可能获得针对上述性状的自发分离克隆。至于细菌金属抗性的可能机制，提出了几种假说，最可信的假说是金属盐的解毒作用。

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