Cenci G, Morozzi G, Daniele R, Scazzocchio F
Ann Sclavo. 1980 Mar-Apr;22(2):212-26.
The incidence and the patterns of the antibiotic and metal resistance in 106 strains of Escherichia coli isolated from ground waters, used also as drinking water supply (sample A), was studied in comparison with the resistance behaviour in the 104 strains of the same microorganism isolated from non hospitalized patients (sample P). Significant differences between the percentage of resistant strains in the two examined samples were found for some of the antibiotics and the metals tested (ampicillin, streptomycin, kanamycin, mercury and zinc) while non statistically significant differences were found for gentamicin, tetracyclin, nalidixic acid and cadmium. From the high percentages of the resistant strains in the environmental sample (up to 44.3% for tetracyclin) we may deduce that also the ground waters, especially if used as drinking water, contribute to the spread of the resistant bacteria. The patterns of the antibiotic multiresistances in the strains isolated from patients and from ground waters do not differ greatly and this strengthens the hypothesis that resistance to antibiotics has been acquired by Escherichia coli strains before reaching the ground waters.
对从也用作饮用水源的地下水中分离出的106株大肠杆菌（样本A）的抗生素和金属抗性的发生率及模式进行了研究，并与从非住院患者中分离出的104株相同微生物（样本P）的抗性行为进行了比较。在所检测的一些抗生素和金属（氨苄青霉素、链霉素、卡那霉素、汞和锌）方面，发现两个检测样本中抗性菌株的百分比存在显著差异，而在庆大霉素、四环素、萘啶酸和镉方面未发现统计学上的显著差异。从环境样本中抗性菌株的高百分比（四环素高达44.3%）可以推断，地下水，尤其是用作饮用水时，也会促使抗性细菌传播。从患者和地下水中分离出的菌株的抗生素多重抗性模式差异不大，这强化了这样一种假设，即大肠杆菌菌株在进入地下水之前就已获得了对抗生素的抗性。
