Rizzo G, Di Biase C
Ann Sclavo. 1976 Nov-Dec;18(6):841-8.
A total of 933 strains of Escherichia coli, of which 146 isolated from cystitis cases, 515 from infantile enteritis one and 272 from healthy individuals, have been chicked for haemolytic activity. A good 45.2% of the strains from the urinary tract, but only 7.7% of the enteritogenic and 3.6% of enteric commensal ones were found to be haemolytic. Among the cystitis strains, a high number (30/146 with an incidence of 20.5%) belonged to O6 serogroup. Serotype O4 was also frequently found (9.5%). Among the urinary strains, of which more than half (53.4%) were included in O1 up to O10 serogroups, the haemolytic ones were comprised in O2, O4, O6, O55 and O75 serogroups. Finally, the Authors point out the importance that the haemolytic activity of Escherichia coli may have in the pathogenesis of the renal injury at the light of some late experimental works.
总共检测了933株大肠杆菌的溶血活性，其中146株分离自膀胱炎病例，515株分离自婴儿肠炎病例，272株分离自健康个体。结果发现，来自泌尿道的菌株中有45.2%具有溶血活性，而致肠炎菌株中只有7.7%，肠道共生菌株中只有3.6%具有溶血活性。在膀胱炎菌株中，有相当数量（30/146，发生率为20.5%）属于O6血清群。O4血清型也很常见（9.5%）。在泌尿道菌株中，超过一半（53.4%）属于O1至O10血清群，其中具有溶血活性的菌株包括在O2、O4、O6、O55和O75血清群中。最后，作者根据一些最新的实验研究指出了大肠杆菌的溶血活性在肾损伤发病机制中可能具有的重要性。
