Mañé J M, Estapé J, Sánchez-Lloret J, Grau J J, Palombo H, Agusti C, Mellado B
Servei de Coordinació Oncologica, Hospital Clinic, Barcelona, Spain.
Age Ageing. 1994 Jan;23(1):28-31. doi: 10.1093/ageing/23.1.28.
A review has been conducted of 1433 patients treated by the Lung Cancer Unit of our hospital to assess the association of age with clinical characteristics of patients with lung cancer. The factors evaluated were tobacco, stage of disease, treatment and survival of patients treated surgically. A comparison was made of patients aged 65 or less with those over 65. There was a similar prevalence of smokers in both age groups. The stage of disease at time of diagnosis was similar (33% of the patients aged 65 or less were Stage I or II versus 37% of the older patients). The distribution by histological type showed significant differences (p < 0.05) with a higher percentage of squamous carcinoma in the younger group (54% versus 44%). Surgery was performed in 30% of the patients aged 65 years or less but only in 19% of the older cases (p < 0.05). Among those patients treated surgically there was no difference in the survival of younger and older patients.
我们对我院肺癌科治疗的1433例患者进行了一项回顾性研究，以评估年龄与肺癌患者临床特征之间的关联。评估的因素包括吸烟情况、疾病分期、治疗方法以及接受手术治疗患者的生存率。对65岁及以下患者与65岁以上患者进行了比较。两个年龄组的吸烟者患病率相似。诊断时的疾病分期相似（65岁及以下患者中33%为Ⅰ期或Ⅱ期，老年患者中这一比例为37%）。组织学类型分布存在显著差异（p<0.05），年轻组鳞状细胞癌的比例更高（54%对44%）。65岁及以下患者中有30%接受了手术治疗，而老年患者中这一比例仅为19%（p<0.05）。在接受手术治疗的患者中，年轻患者和老年患者的生存率没有差异。
