Paulson E K, McClellan J S, Washington K, Spritzer C E, Meyers W C, Baker M E
Department of Radiology, Duke University Medical Center, Durham, NC 27710.
AJR Am J Roentgenol. 1994 Jul;163(1):113-6. doi: 10.2214/ajr.163.1.8010195.
The purpose of this study was to describe the MR appearance of hepatic adenomas and correlate the MR imaging features with pathologic findings.
MR examinations were performed in 14 patients with 66 hepatic adenomas. The diagnosis of hepatic adenoma was proved pathologically in nine patients (22 lesions). In five other patients (44 lesions), who had type I glycogen storage disease and were known to be at risk for hepatic adenomas, the diagnosis was established by repeated sonographic examinations that showed stability, reduction, or resolution of hepatic tumors. T1- and T2-weighted spin-echo MR images obtained at 1.5 T were retrospectively reviewed for the signal intensity of the lesions relative to liver, the signal pattern, the presence of a capsule, and the presence of hemorrhage. Histopathologic specimens (22 lesions) were reviewed for fat content (graded 0-3), the presence of a capsule, and the presence of hemorrhage.
On T1-weighted images, 51 (77%) of 66 lesions were hyperintense, 11 (17%) were hypointense, and four (6%) were isointense with respect to liver. On T2-weighted images, 49 (74%) of 66 lesions were hyperintense, 12 (18%) were isointense, and five (8%) were hypointense. Sixty-one (92%) of 66 lesions were heterogeneous. Eleven (17%) of 66 lesions were hemorrhagic. Of the 22 lesions reviewed histopathologically, 17 were hyperintense on T1-weighted images; 15 of these had a fat content of grade 2 or 3 and two had hemorrhage. All 15 lesions that had a fat content of grade 2 or 3 were hyperintense on T1-weighted images.
Hepatic adenomas have a variable MR appearance but most often are hyperintense with respect to liver on T1- and T2-weighted images. The high signal intensity often relates to the increased fat content of these lesions.
本研究旨在描述肝腺瘤的磁共振成像（MR）表现，并将MR成像特征与病理结果相关联。
对14例患有66个肝腺瘤的患者进行了MR检查。9例患者（22个病灶）经病理证实为肝腺瘤。另外5例患者（44个病灶）患有I型糖原贮积病，已知有患肝腺瘤的风险，通过重复超声检查显示肝肿瘤稳定、缩小或消退而确诊。回顾性分析在1.5T下获得的T1加权和T2加权自旋回波MR图像，观察病灶相对于肝脏的信号强度、信号模式、包膜的存在以及出血情况。对组织病理学标本（22个病灶）进行脂肪含量（0 - 3级）、包膜的存在以及出血情况的评估。
在T1加权图像上，66个病灶中有51个（77%）相对于肝脏呈高信号，11个（17%）呈低信号，4个（6%）呈等信号。在T2加权图像上，66个病灶中有49个（74%）呈高信号，12个（18%）呈等信号，5个（8%）呈低信号。66个病灶中有61个（92%）信号不均匀。66个病灶中有11个（17%）有出血。在22个经组织病理学评估的病灶中，17个在T1加权图像上呈高信号；其中15个脂肪含量为2级或3级，2个有出血。所有脂肪含量为2级或3级的15个病灶在T1加权图像上均呈高信号。
肝腺瘤的MR表现多样，但在T1加权和T2加权图像上相对于肝脏大多呈高信号。高信号强度通常与这些病灶中脂肪含量增加有关。
