Paterson S J, Byrne P J, Molesky M G, Seal R F, Finucane B T
Department of Anesthesia, Walter C. Mackenzie Health Sciences Centre, University of Alberta, Edmonton, Canada.
Anesthesiology. 1994 Jun;80(6):1248-53; discussion 27A.
For a newborn requiring positive-pressure ventilation (PPV), the American Heart Association recommends bag-and-mask ventilation, a challenging procedure for those inexperienced in neonatal resuscitation. The objective of this prospective study was to evaluate the laryngeal mask airway (LMA) as an alternative method of airway management in neonates requiring PPV at birth.
With the approval of the institutional ethics committee, consent was obtained from women in labor at a tertiary care-perinatal center. Inclusion criteria consisted of an expected birth weight of at least 2.5 kg, gestational age of at least 35 weeks, and resuscitation requiring PPV. Neonates meeting these criteria were resuscitated with PPV by means of the LMA. The ease of insertion, number of attempts required, time to establish effective ventilation, skin color, heart rate, respiratory effort, and Apgar scores were recorded.
Attendance by the investigators at delivery was achieved in 93 cases, with 21 meeting the inclusion criteria. In all cases, the LMA was successfully inserted on the first attempt and provided a clinically patent airway. Twenty neonates were successfully resuscitated with the LMA to provide PPV, with no complications directly attributable to its use. One neonate required LMA removal and tracheal intubation to facilitate administration of epinephrine; data from this case was removed from the study.
Providing PPV at birth via a size-1 LMA is effective and easily learned by personnel with expertise in neonatal resuscitation. The LMA should be further assessed as an alternative to bag-and-mask ventilation for this purpose.
对于需要正压通气(PPV)的新生儿,美国心脏协会推荐使用面罩气囊通气,这对于新生儿复苏经验不足的人来说是一项具有挑战性的操作。这项前瞻性研究的目的是评估喉罩气道(LMA)作为出生时需要PPV的新生儿气道管理的替代方法。
经机构伦理委员会批准,在一家三级围产期护理中心获得了分娩妇女的同意。纳入标准包括预期出生体重至少2.5千克、胎龄至少35周以及需要PPV进行复苏。符合这些标准的新生儿通过LMA进行PPV复苏。记录插入的难易程度、所需尝试次数、建立有效通气的时间、肤色、心率、呼吸努力和阿氏评分。
研究人员参与了93例分娩,其中21例符合纳入标准。在所有病例中,LMA首次尝试插入均成功,并提供了临床上通畅的气道。20例新生儿通过LMA成功复苏以提供PPV,没有直接归因于其使用的并发症。1例新生儿需要移除LMA并进行气管插管以方便给予肾上腺素;该病例的数据从研究中剔除。
通过1号LMA在出生时提供PPV是有效的,并且新生儿复苏专业人员很容易学会。为此,应进一步评估LMA作为面罩气囊通气替代方法的可行性。