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尿可替宁作为哮喘儿童被动吸烟暴露的一项指标。

Urinary cotinine as a measure of passive smoke exposure in asthmatic children.

作者信息

Ogborn C J, Duggan A K, DeAngelis C

机构信息

Department of Pediatrics, Johns Hopkins Hospital, Baltimore, Maryland 21287-3144.

出版信息

Clin Pediatr (Phila). 1994 Apr;33(4):220-6. doi: 10.1177/000992289403300406.

DOI:10.1177/000992289403300406
PMID:8013169
Abstract

This study sought to determine (1) the association between passive smoke exposure and acute symptoms in asthmatic children and (2) the association between parental report and objective measures of passive smoke exposure. Asthmatic children ages 3 to 11 were eligible for the study, which involved measurement of smoke exposure by questionnaire and by urine sample at a time of an acute asthma attack and then later when the child was symptom-free. High levels of passive smoke exposure were detected at both times in most children. Parental report of passive smoke exposure correlated with urinary measure of exposure.

摘要

本研究旨在确定

(1)哮喘儿童被动吸烟暴露与急性症状之间的关联;(2)家长报告与被动吸烟暴露客观测量之间的关联。3至11岁的哮喘儿童符合该研究条件,研究包括在急性哮喘发作时通过问卷调查和尿液样本测量烟雾暴露情况,随后在儿童无症状时再次测量。大多数儿童在两个时间点均检测到高水平的被动吸烟暴露。家长对被动吸烟暴露的报告与尿液暴露测量结果相关。

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Reported measures of environmental tobacco smoke exposure: trials and tribulations.已报道的环境烟草烟雾暴露测量方法:试验与磨难
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