Baba S, Nakai K
Second Department of Surgery, Hamamatsu University School of Medicine, Shizuoka, Japan.
J Gastroenterol. 1995 Nov;30 Suppl 8:135-8.
Strictureplasty has recently been advocated in the treatment of obstructive strictures of the small bowel in patients with Crohn's disease. In this group study, results for 69 patients with Crohn's disease who underwent strictureplasty were analyzed by sending questionnaires to 13 institutions belonging to the Research Committee of Inflammatory Bowel Disease of the Japanese Ministry of Health and Welfare. No mortality and anastomotic leakage were observed. Strictureplasties of both the Heineke-Mikulicz and Finney varieties were considered to be safe procedures, even though the sutures had to be applied at the slightly inflammed site. The median follow up was 37 months (range, 0-133 months), and 12 patients needed reoperation. The cumulative 3-year operation-free rate was 92.5% and the 5-year rate was 70.3%. The site of the lesion, the strictureplasty procedure, and previous history of small bowel resection did not significantly influence the operation-free intervals. The cumulative 5-year operation-free rate of the group treated with home elemental enteral nutrition (83.3%) was better than that of the non-treated group (65.3%). Strictureplasty was found to be a safe and effective surgical procedure for high-risk patients with Crohn's disease in whom an appropriate length of bowel should be saved.
近年来,狭窄成形术被推荐用于治疗克罗恩病患者的小肠梗阻性狭窄。在这项分组研究中,通过向日本厚生省炎症性肠病研究委员会所属的13家机构发送调查问卷,对69例行狭窄成形术的克罗恩病患者的结果进行了分析。未观察到死亡和吻合口漏。尽管缝线必须应用于稍有炎症的部位,但海涅克-米库利奇(Heineke-Mikulicz)和芬尼(Finney)两种术式的狭窄成形术都被认为是安全的手术。中位随访时间为37个月(范围0 - 133个月),12例患者需要再次手术。3年累计无手术率为92.5%,5年为70.3%。病变部位、狭窄成形术式以及既往小肠切除史对无手术间隔时间无显著影响。接受家庭要素肠内营养治疗组的5年累计无手术率(83.3%)优于未治疗组(65.3%)。对于需要保留适当肠段长度的高危克罗恩病患者,狭窄成形术是一种安全有效的手术方法。