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在小肠克罗恩病中,长段狭窄成形术与短段狭窄成形术一样安全有效。

Long strictureplasty is as safe and effective as short strictureplasty in small-bowel Crohn's disease.

作者信息

Shatari T, Clark M A, Yamamoto T, Menon A, Keh C, Alexander-Williams J, Keighley M

机构信息

Department of Surgery, Queen Elizabeth Hospital, Edgbaston B15 2TH, UK.

出版信息

Colorectal Dis. 2004 Nov;6(6):438-41. doi: 10.1111/j.1463-1318.2004.00664.x.

Abstract

BACKGROUND

For the past 20 years it has been shown that intestinal strictureplasty is safe and effective in the management of short strictureplasty. Long strictureplasty (> 20 cm) may be an alternative to resection in some patients, especially in diffuse disease or after previous extensive resections. We reviewed the outcome of long strictureplasty for Crohn's Disease, to examine safety and recurrence rates, compared with conventional short strictureplasty.

METHODS

Sixty-two patients have undergone single strictureplasty for jejunoileal Crohn's disease since 1974. Median follow-up was 121 (range 7-253) months. Twenty-one operations involved a single long strictureplasty, and 41 operations had a single short strictureplasty.

RESULTS

No significant differences were identified between the groups. The postoperative complications in long strictureplasty included 2 abscesses only and after short strictureplasty there was one anastomotic leak and one postoperative abscess. The median hospital stay was 10 days after long strictureplasty and 9 days after short strictureplasty. Three-, 5- and 10-year disease-free rates for long and short strictureplasty, respectively, were 3-year 80.4% and 62.1%; 5-year 55.2% and 49.8% and 10-year 49.1% and 33.5% (NS).

CONCLUSIONS

These data indicate that long strictureplasty is safe and produces equivalent results to conventional (short) strictureplasty.

摘要

背景

在过去20年中,已表明肠狭窄成形术在处理短段狭窄成形方面是安全有效的。长段狭窄成形术(>20 cm)在某些患者中可能是切除术的替代方法,尤其是在弥漫性疾病患者或先前进行过广泛切除术后的患者中。我们回顾了克罗恩病长段狭窄成形术的结果,以检查其安全性和复发率,并与传统的短段狭窄成形术进行比较。

方法

自1974年以来,62例患者因空肠回肠克罗恩病接受了单次狭窄成形术。中位随访时间为121(范围7 - 253)个月。21例手术涉及单次长段狭窄成形术,41例手术进行了单次短段狭窄成形术。

结果

两组之间未发现显著差异。长段狭窄成形术的术后并发症仅包括2例脓肿,短段狭窄成形术后有1例吻合口漏和1例术后脓肿。长段狭窄成形术后中位住院时间为10天,短段狭窄成形术后为9天。长段和短段狭窄成形术的3年、5年和10年无病生存率分别为:3年80.4%和62.1%;5年55.2%和49.8%;10年49.1%和33.5%(无显著性差异)。

结论

这些数据表明,长段狭窄成形术是安全的,并且产生的结果与传统(短段)狭窄成形术相当。

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