Chuĭkova K I, Vasil'ev N V
Zh Mikrobiol Epidemiol Immunobiol. 1994 Jan-Feb(2):40-4.
The quantitative characteristics of T and B-lymphocytes and their subpopulations (theophylline-resistant and theophylline-sensitive lymphocytes), the reaction of lymphocyte blast transformation (RLBT) after stimulation with phytohemagglutinin (PHA) and the level of circulating immune complexes (CIC) in pseudotuberculosis patients with and without concomitant opisthorchiasis were studied and compared. For control opisthorchiasis patients undergoing dehelminthization and healthy persons were examined. The following results were obtained: in most pseudotuberculosis patients Opisthorchis invasion contributed to the formation of stable and prolonged T lymphopenia, an increase in the content of theophylline-sensitive lymphocytes and CIC, hyporeactivity of T lymphocytes in RLBT. Immunodeficiency developing in chronic opisthorchiasis is reversible, i.e. successful dehelminthization leads to the normalization of immunological characteristics.
研究并比较了伴有和不伴有并发后睾吸虫病的假结核病患者中T淋巴细胞和B淋巴细胞及其亚群（茶碱抵抗性和茶碱敏感性淋巴细胞）的定量特征、植物血凝素（PHA）刺激后淋巴细胞母细胞转化反应（RLBT）以及循环免疫复合物（CIC）水平。以接受驱虫治疗的后睾吸虫病患者和健康人为对照进行检查。获得了以下结果：在大多数假结核病患者中，后睾吸虫感染导致稳定且持久的T淋巴细胞减少、茶碱敏感性淋巴细胞和CIC含量增加、RLBT中T淋巴细胞反应性降低。慢性后睾吸虫病中出现的免疫缺陷是可逆的，即成功驱虫可使免疫特征恢复正常。
