Bezuglova M S, Rusakova E V, Drynov I D, Frank K D
Zh Mikrobiol Epidemiol Immunobiol. 1994 Jan-Feb(2):45-9.
Measles morbidity and the state of the immune stratum among children during pre-epidemic, epidemic and post epidemic periods, taken separately, has been analyzed by a specially developed method of statistical analysis. With the immune stratum remaining the same, differences in morbidity rates in different years of the cycle have been revealed. The study has demonstrated that in the presence of a high level of the immune stratum measles morbidity retains its cyclic character, which may be attributed to the action of other factors on this process. Morbidity rate has been found to be influenced by such factor as the frequency of contacts with the source of infection, and in this connection the risk of contacting measles by nonimmune children varies in different age groups of children. Regressive equations have been constructed on the basis of the above approach, thus permitting the prognostication of measles morbidity for the coming year in individual groups of children, which is of importance for the scientifically substantiated and oriented correction of antiepidemic measures.
采用专门开发的统计分析方法,分别对麻疹发病情况以及儿童在流行前、流行期间和流行后阶段的免疫层状况进行了分析。在免疫层保持不变的情况下,揭示了周期中不同年份发病率的差异。该研究表明,在免疫层水平较高的情况下,麻疹发病率仍保持其周期性特征,这可能归因于其他因素对这一过程的作用。已发现发病率受与感染源接触频率等因素影响,在这方面,非免疫儿童感染麻疹的风险在不同年龄组儿童中有所不同。基于上述方法构建了回归方程,从而能够对个别儿童群体来年的麻疹发病率进行预测,这对于科学合理且有针对性地调整防疫措施具有重要意义。