Cook N J, Dapling R B
Department of Ophthalmology, Royal Hallamshire Hospital, Sheffield, U.K.
Acta Ophthalmol (Copenh). 1994 Feb;72(1):124-5. doi: 10.1111/j.1755-3768.1994.tb02751.x.
The exact pathogenesis of pterygia is not yet clearly understood. Most recent studies implicate fibroblastic proliferation as the essential histopathology in the condition. A case is presented in which spontaneous avulsion of the head of a pterygium occurred, with rapid resolution of symptoms. Such an avulsion suggests the presence of strong forces being exerted on the cornea by the pterygium. Fibroblastic activity could be responsible for the development of such forces. This case supports existing evidence for the primary nature of fibroblastic proliferation in the development of pterygia.
翼状胬肉的确切发病机制尚未完全明确。最近的研究表明成纤维细胞增殖是该病的基本组织病理学特征。本文报告了一例翼状胬肉头部自发性撕脱且症状迅速缓解的病例。这种撕脱提示翼状胬肉对角膜施加了强大的作用力。成纤维细胞活性可能是产生这种作用力的原因。该病例支持了现有证据,即成纤维细胞增殖在翼状胬肉形成过程中具有原发性。