Reilly S L, Sing C F, Savageau M A, Turner S T
University of Michigan Medical School, Ann Arbor.
Integr Physiol Behav Sci. 1994 Jan-Mar;29(1):55-73. doi: 10.1007/BF02691281.
In this article we present a new methodology--Biochemical Systems Theory and Analysis--as an alternative to traditional parametric statistical procedures for investigating differences between risk groups in a population. We review the systems theory and how it can be used to represent a model of processes influencing renal hemodynamics and sodium (Na+) excretion. We also discuss the potential for new measures of the biology of common diseases that can emerge from a synergism between systems theory and population-based statistical approaches.
在本文中，我们提出一种新方法——生化系统理论与分析，作为传统参数统计程序的替代方法，用于研究人群中风险组之间的差异。我们回顾了系统理论及其如何用于表示影响肾血流动力学和钠（Na+）排泄过程的模型。我们还讨论了系统理论与基于人群的统计方法之间协同作用可能产生的常见疾病生物学新测量方法的潜力。
