Morokov V A
Gematol Transfuziol. 1993 Feb;38(2):36-40.
A general situation in transfusiology influencing sensitization probability greatly differs from that in a panmictic population as blood transfusions are strictly controlled by ABO group and Factor D rhesus. However, with increasing hemotransfusion scope, clinical significance shifts to other factors, "minor" antigens of erythrocytes, which are not given due attention in hemotransfusions. Besides ABO factors and antigen D rhesus in practical transfusiology of importance are antigens C, c, E, e, K allosensitization to which is mainly observed in rhesus-positive subjects.
输血学中影响致敏概率的总体情况与随机交配人群有很大不同，因为输血严格受ABO血型和D因子恒河猴血型控制。然而，随着输血范围的扩大，临床意义转向其他因素，即红细胞的“次要”抗原，这些抗原在输血中未得到应有的重视。除了ABO因子和D因子恒河猴血型外，在实际输血学中重要的抗原还有C、c、E、e、K，对这些抗原的同种致敏主要见于恒河猴血型阳性的受试者。
