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43个序列标签位点(STSs)在人类6号染色体上的物理图谱构建。

Physical mapping of 43 STSs to human chromosome 6.

作者信息

Orphanos V, Santibanez-Koref M, McGown G, Hey Y, Rackstraw C, Boyle J M

机构信息

Cancer Research Campaign Department of Cancer Genetics, Christie CRC Research Centre, Manchester, United Kingdom.

出版信息

Genomics. 1994 Mar 15;20(2):301-4. doi: 10.1006/geno.1994.1172.

Abstract

We have localized 43 sequence-tagged sites by deletion mapping using a chromosome 6 panel of 18 translocation hybrids. Thirty-four loci were mapped to the long arm of chromosome 6, and 9 were mapped to 6p. Many of the loci contain (CA)n dinucleotide repeated sequences and therefore will be useful markers for mapping genes on chromosome 6.

摘要

我们利用一个由18个易位杂种组成的6号染色体组通过缺失作图法定位了43个序列标签位点。34个位点被定位到6号染色体长臂,9个被定位到6p。许多位点含有(CA)n二核苷酸重复序列,因此将成为6号染色体上基因作图的有用标记。

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