Santos J I
Department of Infectious Diseases, Hospital Infantil de Mexico Federico Gomez, Mexico City.
Infect Dis Clin North Am. 1994 Mar;8(1):243-67.
The nutritional status of an individual has a profound effect on both host susceptibility to specific infectious diseases and on their outcome. Available data suggest that specific and aggregate nutritional deficiencies can alter a host's immune response and increase susceptibility to infection. From a nutritional point of view, the process of nutrient loss and redistribution has the potential for being exploited to the benefit of the infected malnourished host. The proposal to use nutritional support to bolster the host response to infection in severely ill malnourished patients gains support from the fact that this reiterative cycle of malnutrition and infection is the main cause of morbidity and mortality in children in underdeveloped countries.
个体的营养状况对宿主对特定传染病的易感性及其结局都有深远影响。现有数据表明，特定的和总体的营养缺乏会改变宿主的免疫反应并增加感染易感性。从营养角度来看，营养物质的流失和重新分配过程有可能被利用来造福受感染的营养不良宿主。在重症营养不良患者中使用营养支持来增强宿主对感染的反应这一提议，得到了这样一个事实的支持，即营养不良和感染的这种反复循环是欠发达国家儿童发病和死亡的主要原因。
