Carpenter J P, Owen R S, Holland G A, Baum R A, Barker C F, Perloff L J, Golden M A, Cope C
Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia 19104.
Surgery. 1994 Jul;116(1):17-23.
Successful management of patients with peripheral vascular disease requires detailed vascular imaging, usually performed by contrast arteriography. Recently, magnetic resonance angiography (MRA) has been shown to be a noninvasive technique with greater sensitivity than contrast arteriography for detecting distal runoff vessels in patients with peripheral arterial occlusive disease. However, to supplant the need for contrast arteriography and provide a completely noninvasive evaluation of patients with occlusive disease, accurate imaging of the inflow vessels and the runoff vessels is necessary.
We used both conventional arteriography and MRA in preoperative studies of the aorta, iliac, and femoral vessels of 47 patients. Conventional arteriography and MRA studies were compared for their ability to detect vessel patency and the presence of hemodynamically significant stenoses. Independent interventional plans were developed based on the information provided by each technique. The findings of conventional and MRA studies were verified by intraoperative arteriography or direct operative exploration.
Results of the two studies were identical in 41 (87%) of 47 patients or 600 (98%) of 614 segments imaged. MRA accurately detected patent and occluded arterial segments (sensitivity 99.6%, specificity 100%, positive predictive value 100%, negative predictive value 98.6%) and hemodynamically significant stenoses. Therapeutic plans based on either MRA or conventional arteriography were identical for each patient.
MRA provides comparable results to contrast arteriography in the proximal arterial system and superior results for imaging the distal vasculature. This noninvasive technique may replace contrast arteriography in a large number of patients in the future.
成功治疗外周血管疾病患者需要详细的血管成像,通常通过造影动脉造影来进行。最近,磁共振血管造影(MRA)已被证明是一种非侵入性技术,在检测外周动脉闭塞性疾病患者的远端流出血管方面比造影动脉造影具有更高的灵敏度。然而,为了取代造影动脉造影的需求并提供对闭塞性疾病患者的完全非侵入性评估,对流入血管和流出血管进行准确成像很有必要。
我们在对47例患者的主动脉、髂血管和股血管进行术前研究时同时使用了传统动脉造影和MRA。比较了传统动脉造影和MRA检测血管通畅情况以及血流动力学显著狭窄的能力。根据每种技术提供的信息制定独立的介入计划。传统研究和MRA研究的结果通过术中动脉造影或直接手术探查进行验证。
47例患者中的41例(87%)或614个成像节段中的600个(98%),两项研究结果相同。MRA准确检测出了通畅和闭塞的动脉节段(灵敏度99.6%,特异性100%,阳性预测值100%,阴性预测值98.6%)以及血流动力学显著狭窄。基于MRA或传统动脉造影的治疗计划对每位患者都是相同的。
MRA在近端动脉系统中提供了与造影动脉造影相当的结果,在远端脉管系统成像方面结果更佳。这种非侵入性技术未来可能会在大量患者中取代造影动脉造影。