Dumitru-Stănescu R, Mandravel C, Bercu C
Pneumoconiosis Department, Institute of Hygiene and Public Health, Bucharest, Romania.
Analyst. 1994 Apr;119(4):689-91. doi: 10.1039/an9941900689.
The interaction capacity of asbestos with albumin was studied. Asbestos fibres were treated with bovine serum albumin and were investigated by Fourier transform infrared (IR) spectrometry, conventional IR spectrometry and wide-line nuclear magnetic resonance spectrometry. In asbestos, the presence of active sites on the surface of the fibres was evidenced through external and internal OH stretching vibrations. It was also demonstrated that in asbestos fibres treated with albumin mixed hydrogen bonds of the type O-H...Nalbumin or O...H-Nalbumin occur. A physical interaction between asbestos fibres and albumin was demonstrated.
研究了石棉与白蛋白的相互作用能力。用牛血清白蛋白处理石棉纤维,并通过傅里叶变换红外(IR)光谱、常规IR光谱和宽线核磁共振光谱进行研究。在石棉中,通过外部和内部的OH伸缩振动证明了纤维表面存在活性位点。还表明,在用白蛋白处理的石棉纤维中,存在O-H...N白蛋白或O...H-N白蛋白类型的混合氢键。证明了石棉纤维与白蛋白之间存在物理相互作用。