Duda S H, Wehrmann M, Erdtmann B, Huppert P E, Claussen C D
Department of Diagnostic Radiology, Eberhard-Karls-University, Tübingen, Germany.
Angiology. 1994 Jul;45(7):597-603. doi: 10.1177/000331979404500702.
To define the accuracy of electronic and mechanical ultrasound (US) devices for determining the thickness of intima and media, 32 fresh normal and atherosclerotic human femoral arteries were obtained at necropsy. The samples were imaged with a 64-element array and a mechanically rotating US transducer at 20 MHz. The mean thickness of the intimal and medial layer was measured with electronic calipers followed by histopathologic and micromorphometric analysis. Morphometric correlation for intima showed r = 0.64 for the electronic and r = 0.58 for the mechanical US device. The correlation between ultrasonic and histologic measurement of medial thickness in normal and diseased specimens was r = 0.79 for the multielement and r = 0.76 for the mechanical transducer. In conclusion, multielement array transducers are equivalent to mechanically driven probes in the quantitative assessment of peripheral arterial wall layers. Both systems lack sufficient accuracy in the determination of mild to moderate intimal thickening.
为确定电子和机械超声（US）设备测量内膜和中膜厚度的准确性，在尸检时获取了32条新鲜的正常和动脉粥样硬化的人股动脉。使用64阵元阵列和机械旋转式超声换能器在20MHz频率下对样本进行成像。用电子卡尺测量内膜和中膜层的平均厚度，随后进行组织病理学和微观形态学分析。内膜的形态学相关性显示，电子超声设备的r = 0.64，机械超声设备的r = 0.58。在正常和病变标本中，多阵元超声设备测量中膜厚度与组织学测量之间的相关性r = 0.79，机械换能器的r = 0.76。总之，在对外周动脉壁层的定量评估中，多阵元阵列换能器与机械驱动探头相当。在确定轻度至中度内膜增厚方面，两种系统的准确性均不足。
