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动脉成像:高分辨率超声与磁共振成像的比较及组织学相关性研究

Arterial imaging: comparison of high-resolution US and MR imaging with histologic correlation.

作者信息

Martin A J, Ryan L K, Gotlieb A I, Henkelman R M, Foster F S

机构信息

Department of Medical Biophysics, Sunnybrook Health Science Centre, Ontario, Canada.

出版信息

Radiographics. 1997 Jan-Feb;17(1):189-202. doi: 10.1148/radiographics.17.1.9017808.

DOI:10.1148/radiographics.17.1.9017808
PMID:9017808
Abstract

The potential roles of intravascular ultrasound (US) and magnetic resonance (MR) imaging in evaluating the artery wall and atherosclerotic plaque were compared. Excised human femoral and carotid arteries were imaged with a 42-MHz intravascular US system and a 1.5-T MR imager equipped with enhanced gradients. In-plane resolution was 40-280 microns for US and 156 microns for MR imaging. Stained histologic tissue sections were obtained for correlation with the imaging findings. Intravascular US and MR imaging both had sufficient resolution and contrast to demonstrate arterial layers and allow distinction of atheroma. Correspondence between structures identified with the two modalities was excellent and in agreement with histologically defined arterial structures. Findings on state-of-the-art intravascular US and MR images correlate well with histologic findings in normal and diseased arteries. Intravascular US has the advantages of speed and resolution, whereas MR imaging demonstrates superior contrast in the depiction of atheroma.

摘要

比较了血管内超声(US)和磁共振(MR)成像在评估动脉壁和动脉粥样硬化斑块方面的潜在作用。用42兆赫兹的血管内超声系统和配备增强梯度的1.5特斯拉磁共振成像仪对切除的人股动脉和颈动脉进行成像。血管内超声的平面分辨率为40 - 280微米,磁共振成像为156微米。获取染色的组织学切片以与成像结果进行对照。血管内超声和磁共振成像都具有足够的分辨率和对比度来显示动脉层并区分动脉粥样硬化斑块。两种成像方式所识别结构之间的对应性极佳,且与组织学定义的动脉结构相符。最先进的血管内超声和磁共振图像上的发现与正常和病变动脉的组织学发现密切相关。血管内超声具有速度和分辨率优势,而磁共振成像在描绘动脉粥样硬化斑块方面显示出更好的对比度。

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