Küchle M, Holbach L, Schlötzer-Schrehardt U, Naumann G O
Department of Ophthalmology, University of Erlangen-Nürnberg, Germany.
Br J Ophthalmol. 1994 May;78(5):397-400. doi: 10.1136/bjo.78.5.397.
A 26-year-old man developed a non-pigmented ciliary body tumour of his right eye. A 7 mm block excision and tectonic corneoscleral graft were performed. The excised tissue was studied using histopathological, immunohistochemical, and electron microscopic techniques. The tumour revealed characteristic features of a Schwann cell neoplasm including Antoni A and B patterns, acid mucopolysaccharides, S-100, and vimentin positivity, and--by electron microscopy--Luse bodies. It was classified as a schwannoma. Although rare, schwannoma should be included in the clinical differential diagnosis of non-pigmented ciliary body tumours. Local excision should be considered to avoid over-treatment by enucleation.
一名26岁男性右眼出现了一个无色素的睫状体肿瘤。进行了7毫米的肿物切除及角膜巩膜支撑移植术。使用组织病理学、免疫组织化学和电子显微镜技术对切除的组织进行了研究。肿瘤呈现出施万细胞瘤的特征性表现,包括Antoni A和B型结构、酸性黏多糖、S-100及波形蛋白阳性,并且在电子显微镜下可见Luse小体。该肿瘤被归类为神经鞘瘤。尽管神经鞘瘤罕见,但在无色素睫状体肿瘤的临床鉴别诊断中应予以考虑。应考虑局部切除以避免眼球摘除的过度治疗。