Zighelboim J, Talley N J, Phillips S F
Division of Gastroenterology and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905.
Dig Dis Sci. 1994 Jul;39(7):1441-5. doi: 10.1007/BF02088046.
We aimed to record fundic motor activity in man using the barostat to ascertain if fundic motility is affected by rectal distension. The distal ends of two barostat tubes were placed in the gastric fundus and rectum in 10 healthy volunteers. The gastric bag was first inflated to a constant pressure level that recorded phasic motor activity as changes in volume of the air-filled bag. Baseline motor activity was recorded before, during, and after a 15-min period of constant rectal distension that was clearly perceived by all subjects but was not painful. In all subjects, continuous phasic volume changes, reflecting fundic motor activity, were recorded at a rate of 1-3/min. During rectal distension, a consistent change in mean contractile force of these phasic volume events was not detected; a decrease of more than 30% occurred in only three subjects. We conclude that fundic phasic volume changes are recordable by the barostat, but these are not substantially inhibited by rectal distension.
我们旨在利用压力调节器记录人体胃底的运动活动，以确定胃底运动是否受直肠扩张影响。在10名健康志愿者身上，将两根压力调节器导管的远端分别置于胃底和直肠。首先将胃袋充气至恒定压力水平，通过记录充满空气的胃袋体积变化来记录阶段性运动活动。在所有受试者均能明显感知但不感到疼痛的15分钟持续直肠扩张期间及前后，记录基线运动活动。在所有受试者中，均记录到反映胃底运动活动的连续阶段性体积变化，频率为每分钟1 - 3次。在直肠扩张期间，未检测到这些阶段性体积事件的平均收缩力有一致变化；仅3名受试者出现了超过30%的下降。我们得出结论，压力调节器可记录胃底阶段性体积变化，但直肠扩张并不会对其产生实质性抑制作用。
