Rao D R, Bello H, Warren A P, Brown G E
Department of Food Science and Animal Industries, Alabama A&M University, Normal 35762.
Dig Dis Sci. 1994 Jul;39(7):1519-24. doi: 10.1007/BF02088058.
Ninety-eight adults ranging from 20 to 89 years in age (52 blacks, 46 whites, 48 males, 50 females) were tested for lactose maldigestion by breath hydrogen analysis after consuming milk containing 16.5 g lactose (360 ml milk). Older adults (> or = 50 years) displayed a significantly higher incidence (46%) of lactose maldigestion than younger adults (< 50 years, 26%). In younger adults there were 2.4 times more maldigesters in blacks than in whites, while in older groups this ratio was 3.6. Level of breath hydrogen significantly increased with age up to the age group of 60-69 years. The interaction between age groups and race was highly significant. Of the maldigesters, 63% reported symptoms and 3% of the total sample reported severe symptoms. Results of this study indicate that the prevalance of lactose maldigestion significantly increases with age in blacks compared to whites and that the magnitude of the problem may be greater in black maldigesters than in white maldigesters.
对98名年龄在20至89岁之间的成年人（52名黑人、46名白人、48名男性、50名女性）进行了测试，让他们饮用含有16.5克乳糖（360毫升牛奶）的牛奶后，通过呼气氢分析来检测乳糖消化不良情况。年龄较大的成年人（≥50岁）乳糖消化不良的发生率（46%）显著高于较年轻的成年人（<50岁，26%）。在较年轻的成年人中，黑人乳糖消化不良者的数量是白人的2.4倍，而在年龄较大的群体中，这一比例为3.6。呼气氢水平随年龄增长显著升高，直至60 - 69岁年龄组。年龄组与种族之间的相互作用非常显著。在乳糖消化不良者中，63%报告有症状，占总样本的3%报告有严重症状。本研究结果表明，与白人相比，黑人中乳糖消化不良的患病率随年龄显著增加，而且黑人乳糖消化不良者的问题严重程度可能比白人乳糖消化不良者更大。
